The Patriots are going to be without their two best linemen and run stoppers. Ty Warren and Big Vince Wilfork will not play against the Bills. This is very bad news for the Patriots upfront. The Bills love to run the ball and have two very good backs. Fred Jackson will find a hole and hit it and Marshawn Lynch is a very capable runner (once their starter). With out these two d linemen the Pats will have trouble stopping the run.
The weather is going to be crappy too so the Bills will lean on their run game even more. Last week when Wilfork got hurt the Pats brought in Titus Adams, great name but not a great game. He was pushed off the line with ease. Some one will have to step it up: Mike Wright and Jarvas Green are the two guys that need to. Adalias Thomas might see some time at Defensive End.
Also Fred Taylor is out for the game. Hopefully all three will be back before next week.